If you use the "Combine JavaScript output into file" option in a TypeScript project the debugger does not map the JavaScript code back to the typescript code properly. All JS code is mapped back to a single TS file instead of taking into account the actual TS source file from which the JS was produced. This affects multiple debugging aspects, breakpoints, stack frames, source stepping all exhibit strange behavior.
Comments: http://nodejstools.codeplex.com/workitem/1354
Comments: http://nodejstools.codeplex.com/workitem/1354